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Alternative TitleNanofluidic chip, processing method based on atomic force microscopy (AFM), and application
焦念东; 王志迁; 董再励
Rights Holder中国科学院沈阳自动化研究所
Patent Agent沈阳科苑专利商标代理有限公司 21002
Other AbstractThe invention discloses a nanofluidic chip, a processing method based on atomic force microscopy (AFM), and application. Each of two ends of the chip is provided with a liquid storage tank each liquid storage tank is connected with a micron pipeline a nano pipeline is arranged between two micron pipelines and electrodes which are vertical to the pipelines are arranged on two sides of the nano pipeline. The nano pipeline which is communicated with the micron pipelines is processed by using an AFM probe. Certain voltage is applied between the liquid storage tanks of the chip, small voltage is applied to the electrodes on two sides of the pipelines simultaneously, and the change of a current signal is measured and when an object flows through the electrodes in the nano pipeline, current changes, and signal detection can be used for analyzing the structural and physical characteristics of a nano material. Processing and signal detection methods for the nanofluidic chip can applied to low-cost and quick sequencing of deoxyribose nucleic acid (DNA) molecules.
PCT Attributes
Application Date2010-12-30
Application NumberCN201010614403.7
Open (Notice) NumberCN102539503A
Contribution Rank1
Document Type专利
Recommended Citation
GB/T 7714
焦念东,王志迁,董再励. 一种纳流控芯片及基于AFM的加工方法和应用[P]. 2012-07-04.
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