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题名: Inducing self-rotation of cells with natural and artificial melanin in a linearly polarized alternating current electric field
作者: Ouyang, Mengxing ; Cheung, Wing Ki ; Liang WF(梁文峰) ; Mai, John D. ; Liu, Wing Keung ; Li WR(李文荣)
作者部门: 机器人学研究室
关键词: INSULATOR-BASED DIELECTROPHORESIS ; WALLED CARBON NANOTUBES ; COUPLED ELECTROROTATION ; DIELECTRIC-PROPERTIES ; AC DIELECTROPHORESIS ; DNA NANOPARTICLES ; CANCER-CELLS ; SEPARATION ; CHIP ; ELECTROKINETICS
刊名: BIOMICROFLUIDICS
ISSN号: 1932-1058
出版日期: 2013
卷号: 7, 期号:5
收录类别: SCI ; EI
产权排序: 3
摘要: The phenomenon of self-rotation observed in naturally and artificially pigmented cells under an applied linearly polarized alternating current (non-rotating) electrical field has been investigated. The repeatable and controllable rotation speeds of the cells were quantified and their dependence on dielectrophoretic parameters such as frequency, voltage, and waveform was studied. Moreover, the rotation behavior of the pigmented cells with different melanin content was compared to quantify the correlation between self-rotation and the presence of melanin. Most importantly, macrophages, which did not originally rotate in the applied non-rotating electric field, began to exhibit self-rotation that was very similar to that of the pigmented cells, after ingesting foreign particles (e.g., synthetic melanin or latex beads). We envision the discovery presented in this paper will enable the development of a rapid, non-intrusive, and automated process to obtain the electrical conductivities and permittivities of cellular membrane and cytoplasm in the near future. (C) 2013 AIP Publishing LLC.
语种: 英语
WOS记录号: WOS:000326877600014
WOS标题词: Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
类目[WOS]: Biochemical Research Methods ; Biophysics ; Nanoscience & Nanotechnology ; Physics, Fluids & Plasmas
关键词[WOS]: INSULATOR-BASED DIELECTROPHORESIS ; WALLED CARBON NANOTUBES ; COUPLED ELECTROROTATION ; DIELECTRIC-PROPERTIES ; AC DIELECTROPHORESIS ; DNA NANOPARTICLES ; CANCER-CELLS ; SEPARATION ; CHIP ; ELECTROKINETICS
研究领域[WOS]: Biochemistry & Molecular Biology ; Biophysics ; Science & Technology - Other Topics ; Physics
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内容类型: 期刊论文
URI标识: http://ir.sia.cn/handle/173321/14060
Appears in Collections:机器人学研究室_期刊论文

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