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Alternative TitleRapid template-free cell graphing method
刘连庆; 刘娜; 李文荣; 王越超; 于海波; 董再励
Rights Holder中国科学院沈阳自动化研究所
Patent Agent沈阳科苑专利商标代理有限公司 21002
Other AbstractThe invention relates to a novel cell graphing method, and concretely relates to a cell graphing method based on optically-induced dielectrophoresis (ODEP) technology. The method utilizes the optically-induced dielectrophoresis (ODEP) technology to form pattern-controllable hydrogel on hydrogenated amorphous silicon and is used to control cell growth. A non-uniform electric field induced by a light spot is capable of inducing motion of a micrometer particle and motion of a solution in a solution, and generating the phenomena of dielectrophoresis and an electroosmotic flow. The micropattern preparation method does not need a physical template, and a needed PEGDA hydrogel micropattern can be obtained by designing the light spot directly according to a demanded shape, and the size and the position of the PEGDA hydrogel micropattern can be dynamically controlled. By using the method, the growth position and the growth pattern of cells can be controlled, and influence of microscopic environment on cell behavior can be researched by changing the shape and the size of the PEGDA hydrogel micropattern for adjusting the shape of the cell.
PCT Attributes
Application Date2013-07-22
Application NumberCN201310308469.7
Open (Notice) NumberCN104328084A
Contribution Rank1
Document Type专利
Recommended Citation
GB/T 7714
刘连庆,刘娜,李文荣,等. 一种快速无模板的细胞图形化方法[P]. 2015-02-04.
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