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Investigation of penetration using atomic force microscope: potential biomarkers of cell membrane
Yang RH(杨润怀); Liu LQ(刘连庆); Zhang CL(张常麟); Xi N(席宁); Yang, Jie
Department机器人学研究室
Source PublicationMICRO & NANO LETTERS
ISSN1750-0443
2015
Volume10Issue:5Pages:248-252
Indexed BySCI ; EI
EI Accession number20152100860173
WOS IDWOS:000354459300005
Contribution Rank1
AbstractThe penetration of cell membrane using atomic force microscope (AFM) is studied. The penetration is monitored by AFM, and the penetration force is measured for three types of cells. The dissipated energy of the cell membrane before and after drug treatment is also calculated and analysed. Experimental results indicate that AFM is an efficient tool for measuring and monitoring the penetration of the cell membrane. Results also show that the penetration force differs significantly from each type of cells, indicating that the penetration force is a potential biomarker of cell membrane to distinguish different types of cells. Moreover, the dissipated energy of cell membrane is studied to be a biomarker to indicate the condition of the cell membrane. After the cell membrane is treated with dimethyl sulfoxide, the dissipated energy of cell membrane decreases.
Language英语
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Document Type期刊论文
Identifierhttp://ir.sia.cn/handle/173321/16230
Collection机器人学研究室
Corresponding AuthorYang RH(杨润怀)
Affiliation1.Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, China
2.Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China
3.Department of Mechanical and Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong
Recommended Citation
GB/T 7714
Yang RH,Liu LQ,Zhang CL,et al. Investigation of penetration using atomic force microscope: potential biomarkers of cell membrane[J]. MICRO & NANO LETTERS,2015,10(5):248-252.
APA Yang RH,Liu LQ,Zhang CL,Xi N,&Yang, Jie.(2015).Investigation of penetration using atomic force microscope: potential biomarkers of cell membrane.MICRO & NANO LETTERS,10(5),248-252.
MLA Yang RH,et al."Investigation of penetration using atomic force microscope: potential biomarkers of cell membrane".MICRO & NANO LETTERS 10.5(2015):248-252.
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