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Investigation of penetration using atomic force microscope: potential biomarkers of cell membrane
Yang RH(杨润怀); Liu LQ(刘连庆); Zhang CL(张常麟); Xi N(席宁); Yang, Jie
作者部门机器人学研究室
发表期刊MICRO & NANO LETTERS
ISSN1750-0443
2015
卷号10期号:5页码:248-252
收录类别SCI ; EI
EI收录号20152100860173
WOS记录号WOS:000354459300005
产权排序1
摘要The penetration of cell membrane using atomic force microscope (AFM) is studied. The penetration is monitored by AFM, and the penetration force is measured for three types of cells. The dissipated energy of the cell membrane before and after drug treatment is also calculated and analysed. Experimental results indicate that AFM is an efficient tool for measuring and monitoring the penetration of the cell membrane. Results also show that the penetration force differs significantly from each type of cells, indicating that the penetration force is a potential biomarker of cell membrane to distinguish different types of cells. Moreover, the dissipated energy of cell membrane is studied to be a biomarker to indicate the condition of the cell membrane. After the cell membrane is treated with dimethyl sulfoxide, the dissipated energy of cell membrane decreases.
语种英语
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被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.sia.cn/handle/173321/16230
专题机器人学研究室
通讯作者Yang RH(杨润怀)
作者单位1.Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, China
2.Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China
3.Department of Mechanical and Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong
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Yang RH,Liu LQ,Zhang CL,et al. Investigation of penetration using atomic force microscope: potential biomarkers of cell membrane[J]. MICRO & NANO LETTERS,2015,10(5):248-252.
APA Yang RH,Liu LQ,Zhang CL,Xi N,&Yang, Jie.(2015).Investigation of penetration using atomic force microscope: potential biomarkers of cell membrane.MICRO & NANO LETTERS,10(5),248-252.
MLA Yang RH,et al."Investigation of penetration using atomic force microscope: potential biomarkers of cell membrane".MICRO & NANO LETTERS 10.5(2015):248-252.
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