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Biological applications of a nanomanipulator based on AFM: In situ visualization and quantification of cellular behaviors at the single-molecule level
Li M(李密); Liu LQ(刘连庆); Xi N(席宁); Wang YC(王越超)
作者部门机器人学研究室
发表期刊IEEE Nanotechnology Magazine
ISSN1932-4510
2015
卷号9期号:3页码:25-35
收录类别EI
EI收录号20153401206346
产权排序1
摘要

Cells are the structural and functional unit of living organisms. Knowledge of cellular behaviors is critical for us to understand the underlying mechanisms that guide the physiological and pathological changes in living organisms. So far, virtually all knowledge of the molecular reactions in cells has come from the ensemble measurements done in test tubes with purified molecules [1], [2]. The disadvantage of this approach is that experiments with purified molecules require the lysis of cells, meaning that the obtained results may not reflect the real situations of living cells.

语种英语
文献类型期刊论文
条目标识符http://ir.sia.cn/handle/173321/16902
专题机器人学研究室
通讯作者Li M(李密)
作者单位1.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, China
2.Dept of Electrical and Computer Engineering, Michigan State University, East Lansing, MI, United States
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Li M,Liu LQ,Xi N,et al. Biological applications of a nanomanipulator based on AFM: In situ visualization and quantification of cellular behaviors at the single-molecule level[J]. IEEE Nanotechnology Magazine,2015,9(3):25-35.
APA Li M,Liu LQ,Xi N,&Wang YC.(2015).Biological applications of a nanomanipulator based on AFM: In situ visualization and quantification of cellular behaviors at the single-molecule level.IEEE Nanotechnology Magazine,9(3),25-35.
MLA Li M,et al."Biological applications of a nanomanipulator based on AFM: In situ visualization and quantification of cellular behaviors at the single-molecule level".IEEE Nanotechnology Magazine 9.3(2015):25-35.
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