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A multilayered PDMS based microtas for high-sensitivity insulin detection
Srinivasan, Balaji; Yao P(姚萍); Tung, Steve
作者部门机器人学研究室
会议名称18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
会议日期October 26-30, 2014
会议地点San Antonio, TX, United states
会议主办者Analytical Chemistry; CBMS; Indiana University (IU); Institute of Microchemical Technology (IMT); LPKF Laser and Electronics
会议录名称18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
出版者Chemical and Biological Microsystems Society
2014
页码1969-1971
收录类别EI
EI收录号20153801288883
产权排序2
ISBN号978-0-9798064-7-6
关键词Insulin Detection Impedance Chemiluminescence Micropump Micromixer Biosensor
摘要This paper reports a multilayered, automated PDMS based microTAS for rapid, high-sensitivity and point-of-care insulin detection. Two generations of microTAS differing in their design complexity and insulin detection protocol were compared. The first generation microTAS includes one micropump, one micromixer and interdigitated electrodes to perform flow through impedance spectroscopy for insulin detection with a detection limit of 10-5 M achieved within 20 min. The second generation microTAS includes multiple micropumps and valves, and is based on double antibody sandwich chemiluminescence immunoassay for insulin detection with a detection limit of 2.6 × 10-10 M achieved within 10 min.
语种英语
文献类型会议论文
条目标识符http://ir.sia.cn/handle/173321/16965
专题机器人学研究室
作者单位1.University of Arkansas, United States
2.Shenyang Institute of Automation, China
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GB/T 7714
Srinivasan, Balaji,Yao P,Tung, Steve. A multilayered PDMS based microtas for high-sensitivity insulin detection[C]//Analytical Chemistry; CBMS; Indiana University (IU); Institute of Microchemical Technology (IMT); LPKF Laser and Electronics:Chemical and Biological Microsystems Society,2014:1969-1971.
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