SIA OpenIR  > 机器人学研究室
Alternative TitleMethod for acquiring label-free cells electrical characteristics based on light-induced dielectrophoresis mechanical force
刘连庆; 梁文峰; 李文荣; 张伟京; 肖秀斌
Rights Holder中国科学院沈阳自动化研究所
Patent Agent沈阳科苑专利商标代理有限公司 21002
Other AbstractThe invention relates to a method for acquiring label-free cells electrical characteristics based on light-induced dielectrophoresis mechanical force. The method comprises the following steps: incident light is projected to a lower surface of a photoelectron tweezer chip; frequency of alternating voltage emitted by a signal-generator is affected on a conducting layer of the photoelectron tweezer chip; cells move far from the incident light; frequency of applied alternating voltage can be increased, when certain cell is stationary, the frequency is a cross-over frequency of the cell; frequency of the applied alternating voltage is continuously increased, the cell moves towards to the incident light; when all the cells move in an incident light scope, the incident light and the applied alternating voltage are closed; a relation between the cross-over frequency and a diameter of each cell can be obtained; and capacitance of each cell membrane can be obtained according to the relation between the cell membrane capacitance and cell diameter. The preparation of metal microelectrodes with a specific structure is not required; the electrical characteristic parameter of single cell or many cells can be obtained with real time; an antibody is not required for being used for identification of the cells, and the method has the advantages of automation, mass production and high throughput capacity.
PCT Attributes
Application Date2014-09-19
Application NumberCN201410482823.2
Open (Notice) NumberCN105486867A
Contribution Rank1
Document Type专利
Recommended Citation
GB/T 7714
刘连庆,梁文峰,李文荣,等. 基于光诱导介电泳机械力的免标记细胞电特性获取方法[P]. 2016-04-13.
Files in This Item:
File Name/Size DocType Version Access License
CN201410482823.2.pdf(521KB)专利 开放获取CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[刘连庆]'s Articles
[梁文峰]'s Articles
[李文荣]'s Articles
Baidu academic
Similar articles in Baidu academic
[刘连庆]'s Articles
[梁文峰]'s Articles
[李文荣]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[刘连庆]'s Articles
[梁文峰]'s Articles
[李文荣]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: CN201410482823.2.pdf
Format: Adobe PDF
All comments (0)
No comment.

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.