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Controllable cancer cell growth using UV patterned hydrogels via DMD-based modulating projection printing
Yang WG(杨文广); Yu HB(于海波); Wang YC(王越超); Liu LQ(刘连庆)
Department机器人学研究室
Conference Name15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015
Conference DateJuly 27-30, 2015
Conference PlaceRome, Italy
Author of SourceNanotechnology Council
Source PublicationIEEE-NANO 2015 - 15th International Conference on Nanotechnology
PublisherIEEE
Publication PlacePiscataway, NJ, USA
2015
Pages1410-1413
Indexed ByEI ; CPCI(ISTP)
EI Accession number20161702301466
WOS IDWOS:000380515200282
Contribution Rank1
ISBN978-1-4673-8155-0
KeywordCell Pattern Cell Biology Microfabrication Cell Adhesion Rapid Pattern
AbstractFabrication of cell growth environment in vitro to control the cell spatial arrangement and proliferation is an indispensable technique for cell-based technologies. Previously several developed micropatterning methods such as soft lithography required relatively complicated operations, which leads to difficulties in the following research to investigate the effects of different cell growth patterns. This manuscript introduces a DMD-based projection technique to quickly pattern a poly(ethylene) glycol diacrylate (PEGDA)-based hydrogel on common glass substrates, which were used to control the growth patterns of cells. Compared with other methods, employed with digital dynamic mask, polymerisation of PEGDA solution can be induced to create arbitrary shape microstructures with high efficiency, flexibility and repeatability. The time duration of UV exposure is less than 10 s by controlling the projected illumination pattern. The resistance to cell attachment enables patterned PEGDA-coated film to be employed to hinder cell adhesion while the blank area allowing cells to grow in various patterns and sizes.
Language英语
Citation statistics
Document Type会议论文
Identifierhttp://ir.sia.cn/handle/173321/18611
Collection机器人学研究室
Corresponding AuthorYu HB(于海波); Liu LQ(刘连庆)
Affiliation1.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, 110016, China
2.University of Chinese Academy of Sciences, Beijing, 100049, China
Recommended Citation
GB/T 7714
Yang WG,Yu HB,Wang YC,et al. Controllable cancer cell growth using UV patterned hydrogels via DMD-based modulating projection printing[C]//Nanotechnology Council. Piscataway, NJ, USA:IEEE,2015:1410-1413.
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