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Controllable cancer cell growth using UV patterned hydrogels via DMD-based modulating projection printing
Yang WG(杨文广); Yu HB(于海波); Wang YC(王越超); Liu LQ(刘连庆)
作者部门机器人学研究室
会议名称15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015
会议日期July 27-30, 2015
会议地点Rome, Italy
会议主办者Nanotechnology Council
会议录名称IEEE-NANO 2015 - 15th International Conference on Nanotechnology
出版者IEEE
出版地Piscataway, NJ, USA
2015
页码1410-1413
收录类别EI ; CPCI(ISTP)
EI收录号20161702301466
WOS记录号WOS:000380515200282
产权排序1
ISBN号978-1-4673-8155-0
关键词Cell Pattern Cell Biology Microfabrication Cell Adhesion Rapid Pattern
摘要Fabrication of cell growth environment in vitro to control the cell spatial arrangement and proliferation is an indispensable technique for cell-based technologies. Previously several developed micropatterning methods such as soft lithography required relatively complicated operations, which leads to difficulties in the following research to investigate the effects of different cell growth patterns. This manuscript introduces a DMD-based projection technique to quickly pattern a poly(ethylene) glycol diacrylate (PEGDA)-based hydrogel on common glass substrates, which were used to control the growth patterns of cells. Compared with other methods, employed with digital dynamic mask, polymerisation of PEGDA solution can be induced to create arbitrary shape microstructures with high efficiency, flexibility and repeatability. The time duration of UV exposure is less than 10 s by controlling the projected illumination pattern. The resistance to cell attachment enables patterned PEGDA-coated film to be employed to hinder cell adhesion while the blank area allowing cells to grow in various patterns and sizes.
语种英语
引用统计
文献类型会议论文
条目标识符http://ir.sia.cn/handle/173321/18611
专题机器人学研究室
通讯作者Yu HB(于海波); Liu LQ(刘连庆)
作者单位1.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, 110016, China
2.University of Chinese Academy of Sciences, Beijing, 100049, China
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GB/T 7714
Yang WG,Yu HB,Wang YC,et al. Controllable cancer cell growth using UV patterned hydrogels via DMD-based modulating projection printing[C]//Nanotechnology Council. Piscataway, NJ, USA:IEEE,2015:1410-1413.
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