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Characterization of the self-rotational motion of stored red blood cells by using optically-induced electrokinetics
Liang WF(梁文峰); Wang YC(王越超); Zhang, Hemin; Liu LQ(刘连庆)
作者部门机器人学研究室
发表期刊Optics Letters
ISSN0146-9592
2016
卷号41期号:12页码:2763-2766
收录类别SCI ; EI
EI收录号20162602546714
WOS记录号WOS:000378065900024
产权排序1
资助机构National Natural Science Foundation of China (NSFC) [51405481, 61503258, 61522312]
摘要We report a label-free approach toward the object of characterizing the self-rotational motions of red blood cells (RBCs) during storage under the optically-induced electrokinetics-based microfluidics mechanism. A theoretical analysis of the transmembrane potential across RBCs was performed getting a threshold voltage for keeping cellular biological integrity. Then, by investigation of the self-rotational behaviors of the individual RBCs in larger population, the RBCs that were stored more than three weeks statistically showed the distinctive self-rotational speed. Results verified that the self-rotational biomarkers of the RBCs could be used to label-free reckon the qualities of the stored RBCs in this kind of microfluidics chip. This finding may be further developed as a new criterion to real-time and label-free monitoring of the banked blood qualities, thereby diminishing the blood transfusion venture.
语种英语
WOS标题词Science & Technology ; Physical Sciences
WOS类目Optics
关键词[WOS]OPTOELECTRONIC TWEEZERS ; SINGLE CELLS ; MANIPULATION ; MICROPARTICLES ; DEFORMABILITY ; MICROSCOPY ; MEMBRANE ; STORAGE ; DISEASE
WOS研究方向Optics
引用统计
文献类型期刊论文
条目标识符http://ir.sia.cn/handle/173321/18729
专题机器人学研究室
通讯作者Liu LQ(刘连庆)
作者单位1.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China
2.School of Mechanical Engineering, Shenyang Jianzhu University, Shenyang, 110168, China
3.Department of Neurology, People's Hospital of Liaoning Province, Shenyang 110016, China
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GB/T 7714
Liang WF,Wang YC,Zhang, Hemin,et al. Characterization of the self-rotational motion of stored red blood cells by using optically-induced electrokinetics[J]. Optics Letters,2016,41(12):2763-2766.
APA Liang WF,Wang YC,Zhang, Hemin,&Liu LQ.(2016).Characterization of the self-rotational motion of stored red blood cells by using optically-induced electrokinetics.Optics Letters,41(12),2763-2766.
MLA Liang WF,et al."Characterization of the self-rotational motion of stored red blood cells by using optically-induced electrokinetics".Optics Letters 41.12(2016):2763-2766.
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