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题名: Characterization of the self-rotational motion of stored red blood cells by using optically-induced electrokinetics
作者: Liang WF(梁文峰); Wang YC(王越超); Zhang, Hemin; Liu LQ(刘连庆)
作者部门: 机器人学研究室
刊名: Optics Letters
ISSN号: 0146-9592
出版日期: 2016
卷号: 41, 期号:12, 页码:2763-2766
收录类别: SCI ; EI
产权排序: 1
项目资助者: National Natural Science Foundation of China (NSFC) [51405481, 61503258, 61522312]
摘要: We report a label-free approach toward the object of characterizing the self-rotational motions of red blood cells (RBCs) during storage under the optically-induced electrokinetics-based microfluidics mechanism. A theoretical analysis of the transmembrane potential across RBCs was performed getting a threshold voltage for keeping cellular biological integrity. Then, by investigation of the self-rotational behaviors of the individual RBCs in larger population, the RBCs that were stored more than three weeks statistically showed the distinctive self-rotational speed. Results verified that the self-rotational biomarkers of the RBCs could be used to label-free reckon the qualities of the stored RBCs in this kind of microfluidics chip. This finding may be further developed as a new criterion to real-time and label-free monitoring of the banked blood qualities, thereby diminishing the blood transfusion venture.
语种: 英语
WOS记录号: WOS:000378065900024
WOS标题词: Science & Technology ; Physical Sciences
类目[WOS]: Optics
关键词[WOS]: OPTOELECTRONIC TWEEZERS ; SINGLE CELLS ; MANIPULATION ; MICROPARTICLES ; DEFORMABILITY ; MICROSCOPY ; MEMBRANE ; STORAGE ; DISEASE
研究领域[WOS]: Optics
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sia.cn/handle/173321/18729
Appears in Collections:机器人学研究室_期刊论文

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Recommended Citation:
Liang WF,Wang YC,Zhang, Hemin,et al. Characterization of the self-rotational motion of stored red blood cells by using optically-induced electrokinetics[J]. Optics Letters,2016,41(12):2763-2766.
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