SIA OpenIR  > 机器人学研究室
Imaging and mapping individual target proteins on clinical lymphoma cells by AFM
Li M(李密); Liu LQ(刘连庆); Xi N(席宁); Wang YC(王越超); Wang WX(王文学)
Department机器人学研究室
Conference Name9th IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2015
Conference DateNovember 15-18, 2015
Conference PlaceHonolulu, HI, USA
Author of SourceHuawei Technologies Co., Ltd.; IEEE Nanotechnology Council; RSC Advances of the Royal Society of Chemistry; Shenzhen Academy of Robotics; University of Arkansas; University of California at Santa Cruz
Source Publication9th IEEE International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2015
PublisherIEEE Computer Society
Publication PlaceWashington, DC
2015
Pages84-87
Indexed ByEI
EI Accession number20163002649913
Contribution Rank1
ISSN2159-6964
ISBN978-1-4673-9671-4
AbstractThe wide applications of atomic force microscopy (AFM) in the past decade have contributed much to the field of cell biology, providing a lot of novel insights into cellular behaviors at the nanoscale. However, current AFM studies are commonly performed on cell lines cultured in vitro which are quite different from the cells in the human body. Directly investigating the physiological activities on tumor cells from clinical patients is of great significance for helping us to better understand the actual cellular activities taking place in the clinical environment. Under the fluorescence recognition of specific tumor cell surface marker, we have used AFM to investigate the binding affinity and nanoscale distributions of CD20 target protein directly on tumor cells prepared from the bone marrow of lymphoma patients. The results provide a new idea to develop closer links between laboratory study and clinical practice, which may have potential impacts on diverse fields such as drug evaluation and efficacy prediction.
Language英语
Document Type会议论文
Identifierhttp://ir.sia.cn/handle/173321/18756
Collection机器人学研究室
Corresponding AuthorLiu LQ(刘连庆); Xi N(席宁)
Affiliation1.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, 110016, China
2.Department of Electrical and Computer Engineering, Michigan State University, East Lansing, MI, 48824, United States
Recommended Citation
GB/T 7714
Li M,Liu LQ,Xi N,et al. Imaging and mapping individual target proteins on clinical lymphoma cells by AFM[C]//Huawei Technologies Co., Ltd.; IEEE Nanotechnology Council; RSC Advances of the Royal Society of Chemistry; Shenzhen Academy of Robotics; University of Arkansas; University of California at Santa Cruz. Washington, DC:IEEE Computer Society,2015:84-87.
Files in This Item: Download All
File Name/Size DocType Version Access License
Imaging and mapping (415KB)会议论文 开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Li M(李密)]'s Articles
[Liu LQ(刘连庆)]'s Articles
[Xi N(席宁)]'s Articles
Baidu academic
Similar articles in Baidu academic
[Li M(李密)]'s Articles
[Liu LQ(刘连庆)]'s Articles
[Xi N(席宁)]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Li M(李密)]'s Articles
[Liu LQ(刘连庆)]'s Articles
[Xi N(席宁)]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Imaging and mapping individual target proteins on clinical lymphoma cells by AFM.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.