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Alternative TitleSICM amplitude modulation imaging mode scanning device and method
刘连庆; 李鹏; 李广勇; 王越超; 杨洋; 周磊; 王栋
Rights Holder中国科学院沈阳自动化研究所
Patent Agent沈阳科苑专利商标代理有限公司 21002
Other AbstractThe invention relates to an SICM (Scanning Ion Conductance Microscope) amplitude modulation imaging mode scanning device, comprising a signal generator, a patch clamp amplifier, an effective value conversion circuit, a controller, a probe, an XY nano platform, and a Z-direction nano piezoelectric ceramic element, wherein the signal generator, the patch clamp amplifier, the effective value conversion circuit and the controller are connected in sequence. A method provided by the invention comprises the following steps: the signal generator outputs an alternating current signal to the patch clamp amplifier; the compensation capacitance of the patch clamp amplifier is adjusted; and the effective value conversion circuit calculates the effective value of current amplitude, and feeds the effective value of amplitude back to the controller, and the controller controls the height of the probe in real time according to the effective value of amplitude to realize sample scanning. According to the invention, the alternating current amplitude is used as a feedback value, so the defects of a direct-current mode such as direct-current drift and vulnerability to electrical noise are overcome. Higher modulation frequency is achieved compared with the traditional alternating-current mode, and scanning is accelerated.
PCT Attributes
Application Date2015-01-15
Application NumberCN201510023158.5
Open (Notice) NumberCN105842484A
Contribution Rank1
Document Type专利
Recommended Citation
GB/T 7714
刘连庆,李鹏,李广勇,等. 一种SICM的幅度调制成像模式扫描装置和方法[P]. 2016-08-10.
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