Dyeing wastewater is recognized as one of industrial wastewater which is difficult to treatment. Traditional treatment process usually requires adding a large number of coagulation agents,resulting in a long process,high chemical sludge production,and the activity of subsequent aerobic biological may be inhibited by chemical segments. To solve the above problems,aerobic biochemical process optimization was carried out,and we found that under the suitable conditions of process parameters,aerobic activated sludge has good adaptability to the raw dyeing wastewater,average rate of COD removal efficiency for long run can be up to 65%,can shorten the process flow for the actual printing and dyeing wastewater treatment engineering applications,reduce operating costs,and provide a reference for the best performance of aerobic process.