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题名:
Early predictive factors for lower-extremity motor or sensory deficits and surgical results of patients with spinal tuberculosis: A retrospective study of 329 patients
作者: Wang, Hongwei; Yang, Xiao; shi, Ying; Zhou, Yue; Li, Changqing; Chen, Yu; Yu, Hailong; Wang, Qi; Liu, Jun; Cheng, Jiwei; Zhao YW(赵忆文); Han JD(韩建达); Xiang, Liangbi
作者部门: 机器人学研究室
通讯作者: Wang, Hongwei ; Xiang, Liangbi
关键词: epidemiology ; motor deficits ; predictive factors ; sensory disturbance ; spinal tuberculosis
刊名: MEDICINE
ISSN号: 0025-7974
出版日期: 2016
卷号: 95, 期号:34, 页码:1-7
收录类别: SCI
产权排序: 5
项目资助者: Foundation of the State Key Laboratory of Robotics [2014-O12] ; Medjaden Academy and Research Foundation for Young Scientists [MJR20150013] ; Liaoning Province Doctor Startup Fund [201601196]
摘要: Many studies about the characteristics of spinal tuberculosis (STB) have been published, but none has investigated the predictive factors for lower-extremity motor or sensory deficits (LMSD) in patients with STB.The objective of this study was to find early predictive factors for LMSD and evaluate surgical results of patients with STB.From 2001 through 2010, 329 patients with STB were treated in our department and surgical treatment was performed in 274 patients. The factors assessed included age, sex, duration of symptoms, worsening of illness, clinical symptoms, clinical signs, imaging characteristics, kyphotic angle, Oswestry disability index (ODI), and visual analogue scale (VAS) scores.Of the 329 patients studied, 164 presented with LMSD (the LMSD group), of which 93 patients (28.3%) had motor deficits and 177 patients (53.8%) had sensory disturbance. The other 165 patients were included in the control group (the No LMSD group). Using univariate logistic regression analysis, we found that the sex (P=0.042), age (P=0.001), worsening of sickness (P=0.013), location (P=0.009), and spinal compression (P=0.035) were the risk factors of LMSD. Furthermore, the multivariate logistic regression analysis indicated that age (OR=1.761, 95% CI: 1.227-2.526, P=0.002), worsening of sickness (yes vs no: OR=1.910, 95% CI: 1.161-3.141, P=0.011), location (T vs C: OR=0.204, 95% CI: 0.063-0.662, P=0.008), and spinal compression (yes vs no: OR=1.672, 95% CI: 1.020-2.741, P=0.042) were independent risk factors of LMSD. Surgical treatment was performed in 274 patients. The kyphotic angle improved from 25.89.1 degrees preoperatively to 14.0 +/- 7.6 degrees, with a mean correction of 11.8 +/- 4.0 degrees, and a mean correction loss of 1.5 +/- 1.8 degrees at final visit. There were significant differences between the preoperative and the final ODI and VAS scores in both groups (P<0.001 and P<0.001, respectively).Spinal tuberculosis with cervical or lumbar vertebra involvement among the elder patients with a history of worsening of illness and spinal compression tended to cause LMSD, such as motor deficits or sensory disturbance. We should implement an appropriate treatment regimen to prevent exacerbation of STB such as operation, which can achieve thoroughness of debridement, adequate spinal stabilization, and better functional recovery.
语种: 英语
WOS记录号: WOS:000384032900030
WOS标题词: Science & Technology ; Life Sciences & Biomedicine
类目[WOS]: Medicine, General & Internal
关键词[WOS]: KYPHOTIC DEFORMITY ; POTTS-DISEASE ; EXPERIENCE ; MANAGEMENT ; INSTRUMENTATION ; DEBRIDEMENT
研究领域[WOS]: General & Internal Medicine
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内容类型: 期刊论文
URI标识: http://ir.sia.cn/handle/173321/19267
Appears in Collections:机器人学研究室_期刊论文

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Recommended Citation:
Wang, Hongwei,Yang, Xiao,shi, Ying,et al. Early predictive factors for lower-extremity motor or sensory deficits and surgical results of patients with spinal tuberculosis: A retrospective study of 329 patients[J]. MEDICINE,2016-01-01,95(34):1-7.
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