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题名: Discrimination of the state of MCF-7 cells by multiple cell mechanics
作者: Zhou FY(周富元); Wang WX(王文学); Liu LQ(刘连庆)
作者部门: 机器人学研究室
会议名称: 6th Annual IEEE International Conference on Cyber Technology in Automation, Control and Intelligent Systems, IEEE-CYBER 2016
会议日期: June 19-22, 2016
会议地点: Chengdu, China
会议录: 6th Annual IEEE International Conference on Cyber Technology in Automation, Control and Intelligent Systems, IEEE-CYBER 2016
会议录出版者: IEEE
会议录出版地: Piscataway, NJ, USA
出版日期: 2016
页码: 468-473
收录类别: EI
ISBN号: 978-1-5090-2732-3
关键词: cell mechanics ; MCF-7 cells ; young’s modulus ; energy dissipation
摘要: Cell mechanics indicating the state of cell play an important role in critical activities of the cells. However in recent cell mechanics research, most of researchers only considered the young's modulus and energy dissipation is seldom considered. The existing method of the computation of young's modulus can't also make sure the distance between experimental indentation curve and the theory experimental indentation curve is small. To solve the problems described above, an optimization method of computation of young's modulus has been proposed and an experiment has been carried out. In the experiment force curves were obtained from the MCF-7 cells which has been treated with different concentrations (0ug/ml, 50ug/ml, 100ug/ml, 150ug/ml, 200ug/ml) of resveratrol for 36 hours. Young's modulus and energy dissipation could be obtained from the force curves. The experiment results not only shown that compared with the existing method the proposed method has its superiority in the computation of young's modulus, but also indicated that there is a necessity of considering both Young's modulus and energy dissipation. The results provide an effective method for the computation of cell mechanics and lay a foundation for the drug selection and personalized treatment of diseases.
语种: 英语
产权排序: 1
内容类型: 会议论文
URI标识: http://ir.sia.cn/handle/173321/19301
Appears in Collections:机器人学研究室_会议论文

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Recommended Citation:
Zhou FY,Wang WX,Liu LQ. Discrimination of the state of MCF-7 cells by multiple cell mechanics[C]. 见:6th Annual IEEE International Conference on Cyber Technology in Automation, Control and Intelligent Systems, IEEE-CYBER 2016. Chengdu, China. June 19-22, 2016.
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文件名: Discrimination of the state of MCF-7 cells by multiple cell mechanics.pdf
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