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Integrated vortex micropumps and active micromixers in polymer substrates for automating bio-fluidie manipulation
Lam, Raymond H. W.; Mou L(缪磊); Dong ZL(董再励); Lei, Kin Fong; Li WJ(李文荣); Lam, R.H.W.
作者部门机器人学研究室
会议名称2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
会议日期September 1, 2005 - September 4, 2005
会议地点Shanghai, China
会议录名称Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
出版者IEEE
出版地NEW YORK
2005
页码1297-1300
收录类别EI
EI收录号20070710424460
产权排序2
ISSN号0589-1019
ISBN号978-0-7803-8740-9
关键词Microfluidic System Vortex Micropump Active Micromixer Cellular Detection Surface Plasmon Resonance
摘要This paper presents a microfluidic mixing module array developed for bio-fluid/chemical delivery and mixing. Vortex micropunips, microchannels and pillared-surfaee diaphragm (PSD) active micromixers were successfully integrated into a single polymer-based microfluidic chip, consisting of three mixing modules. The pumping characteristics of the vortex micropump were investigated with both analytical and experimental results. Experiments were also conducted to examine the factors affecting the PSD-based mixing. The integrated mixing module further demonstrated the feasibility of chemical mixing and concentration control. An integrated fluidic system was shown successfully to deliver bio-fluid for real-time SPR based detection. A computer-controlled fluid manipulation system is also proposed for the real-time microfluidic operation control. The digitally controllability of the pumping and mixing operations could potentially improve the accuracy and efficiency, and hence, the functionality of the integrated microfluidic system. © 2005 IEEE.
语种英语
文献类型会议论文
条目标识符http://ir.sia.cn/handle/173321/20015
专题机器人学研究室
通讯作者Lam, R.H.W.
作者单位1.Centre for Micro and Nano Systems, Chinese University of Hong Kong, Hong Kong, Hong Kong
2.Micro and Nano Automation Laboratory, Shenyang Institute of Automation, CAS, China
3.Chinese University of Hong Kong
4.Shenyang Institute of Automation
推荐引用方式
GB/T 7714
Lam, Raymond H. W.,Mou L,Dong ZL,et al. Integrated vortex micropumps and active micromixers in polymer substrates for automating bio-fluidie manipulation[C]. NEW YORK:IEEE,2005:1297-1300.
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