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Towards automating micro cellular detection process using micro vortex pump arrays
Lam, Raymond H.W.; Lei, Kin Fong; Mou L(缪磊); Dong ZL(董再励); Law, Wing Cheung; Suen, Yick Keung; Li WJ(李文荣); Ho, Aaron Ho Pu; Kong, Siu-Kai
作者部门机器人学研究室
会议名称IEEE/ASME International Conference on Advanced Intelligent Mechatronics, AIM
会议日期July 24-28, 2005
会议地点Monterey, United states
会议主办者IEEE Industrial Electronics Society; IEEE Robotics and Automation Society; ASME Dynamic Systems and Control Division
会议录名称Proceedings of the 2005 IEEE/ASME International Conference on Advanced Intelligent Mechatronics, AIM 2005
出版者IEEE
出版地NEW YORK
2005
页码66-71
收录类别EI ; CPCI(ISTP)
EI收录号2005469477496
WOS记录号WOS:000232003500012
产权排序2
ISSN号2159-6255
ISBN号0-7803-9046-6
摘要This paper reports a polymer based microfluidic analysis system integrated with a surface plasmon resonance (SPR) biosensor for detecting the specific binding of biomolecules and qualitatively monitoring of cell adhesion on the sensor surface. Micropumps, microchannels, and SPR biosensor were integrated into a single polymer (PMMA) based microfluidic system. The integrated system has been studied in its potential application in bio-molecules detection and drug discovery. Two experiments, 1) monitoring the reaction between BSA-BSA antibody, and 2) monitoring the activities of living cells in the presence or absence of trypsin in RPMI-1640 medium, were conducted to show the feasibility of real-time cellular and molecular detection. Based on these successful experimental results we have also developed a computer-controllable vortex micropump system that will eventually automate many bio-molecular detection and drug discovery processes. © 2005 IEEE.
语种英语
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文献类型会议论文
条目标识符http://ir.sia.cn/handle/173321/20018
专题机器人学研究室
通讯作者Lam, Raymond H.W.
作者单位1.Centre for Micro and Nano Systems, Chinese University of Hong Kong, Hong Kong, Hong Kong
2.Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China
3.Centre or Advanced Research in Photonics, Chinese University of Kong Kong, Hong Kong, Hong Kong
4.Department of Biochemistry, Chinese University of Hong Kong, Hong Kong, Hong Kong
5.Chinese University of Hong Kong
6.Shenyang Institute of Automation
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Lam, Raymond H.W.,Lei, Kin Fong,Mou L,et al. Towards automating micro cellular detection process using micro vortex pump arrays[C]//IEEE Industrial Electronics Society; IEEE Robotics and Automation Society; ASME Dynamic Systems and Control Division. NEW YORK:IEEE,2005:66-71.
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