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Towards automating micro cellular detection process using micro vortex pump arrays
Lam, Raymond H.W.; Lei, Kin Fong; Mou L(缪磊); Dong ZL(董再励); Law, Wing Cheung; Suen, Yick Keung; Li WJ(李文荣); Ho, Aaron Ho Pu; Kong, Siu-Kai
Department机器人学研究室
Conference NameIEEE/ASME International Conference on Advanced Intelligent Mechatronics, AIM
Conference DateJuly 24-28, 2005
Conference PlaceMonterey, United states
Author of SourceIEEE Industrial Electronics Society; IEEE Robotics and Automation Society; ASME Dynamic Systems and Control Division
Source PublicationProceedings of the 2005 IEEE/ASME International Conference on Advanced Intelligent Mechatronics, AIM 2005
PublisherIEEE
Publication PlaceNEW YORK
2005
Pages66-71
Indexed ByEI ; CPCI(ISTP)
EI Accession number2005469477496
WOS IDWOS:000232003500012
Contribution Rank2
ISSN2159-6255
ISBN0-7803-9046-6
AbstractThis paper reports a polymer based microfluidic analysis system integrated with a surface plasmon resonance (SPR) biosensor for detecting the specific binding of biomolecules and qualitatively monitoring of cell adhesion on the sensor surface. Micropumps, microchannels, and SPR biosensor were integrated into a single polymer (PMMA) based microfluidic system. The integrated system has been studied in its potential application in bio-molecules detection and drug discovery. Two experiments, 1) monitoring the reaction between BSA-BSA antibody, and 2) monitoring the activities of living cells in the presence or absence of trypsin in RPMI-1640 medium, were conducted to show the feasibility of real-time cellular and molecular detection. Based on these successful experimental results we have also developed a computer-controllable vortex micropump system that will eventually automate many bio-molecular detection and drug discovery processes. © 2005 IEEE.
Language英语
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Document Type会议论文
Identifierhttp://ir.sia.cn/handle/173321/20018
Collection机器人学研究室
Corresponding AuthorLam, Raymond H.W.
Affiliation1.Centre for Micro and Nano Systems, Chinese University of Hong Kong, Hong Kong, Hong Kong
2.Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China
3.Centre or Advanced Research in Photonics, Chinese University of Kong Kong, Hong Kong, Hong Kong
4.Department of Biochemistry, Chinese University of Hong Kong, Hong Kong, Hong Kong
5.Chinese University of Hong Kong
6.Shenyang Institute of Automation
Recommended Citation
GB/T 7714
Lam, Raymond H.W.,Lei, Kin Fong,Mou L,et al. Towards automating micro cellular detection process using micro vortex pump arrays[C]//IEEE Industrial Electronics Society; IEEE Robotics and Automation Society; ASME Dynamic Systems and Control Division. NEW YORK:IEEE,2005:66-71.
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