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Applications of Micro/Nano Automation Technology in Detecting Cancer Cells for Personalized Medicine
Li M(李密); Liu LQ(刘连庆); Xi N(席宁); Wang YC(王越超)
Department机器人学研究室
Source PublicationIEEE TRANSACTIONS ON NANOTECHNOLOGY
ISSN1536-125X
2017
Volume16Issue:2Pages:217-229
Indexed BySCI ; EI
EI Accession number20171203477399
WOS IDWOS:000396396300009
Contribution Rank1
Funding OrganizationNational Natural Science Foundation of China [61503372, 61522312, 61327014, 61433017] ; Youth Innovation Promotion Association CAS [2017243] ; CAS FEA International Partnership Program for Creative Research Teams
KeywordCancer Cell Micro/nano Automation Personalized Medicine Robotics
AbstractThe coming era of personalized cancer treatment is presenting automation with unprecedented opportunities. Currently, the drug susceptibility test of clinical cancer patients is mainly dependent on manual labor with a low level of automation. Automating the process of primary cancer cell detection will potentially have tremendous economic benefits and social significance. Automated cancer cell detection means developing robotic and automation equipments to handle single cells and molecules at the micro/nanometer-scale. The achievements of information science, engineering technology, life sciences, and nanotechnology in the past decades have led to the birth of robots that can perform effective manipulations on single living cells at the micro/nanometerscale in aqueous conditions, opening the door to automated cancer cell detection. However, there is still a huge gap between current single-cell micro/nano automation technology and clinical requirements for personalized medicine. In this paper, we will review the progress of single-cell micro/nano automation technology in recent years and discuss the facing challenges and future directions in three aspects, including automated cell isolation and delivery, automatically acquiring the physiological features of cells and data analysis.
Language英语
WOS HeadingsScience & Technology ; Technology ; Physical Sciences
WOS SubjectEngineering, Electrical & Electronic ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied
WOS KeywordATOMIC-FORCE MICROSCOPY ; CIRCULATING TUMOR-CELLS ; LABEL-FREE ISOLATION ; ON-A-CHIP ; LIVING CELLS ; SAMPLE PREPARATION ; ANTIBODY THERAPY ; CELLULAR-LEVEL ; SINGLE CELLS ; AFM
WOS Research AreaEngineering ; Science & Technology - Other Topics ; Materials Science ; Physics
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Cited Times:9[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sia.cn/handle/173321/20241
Collection机器人学研究室
Corresponding AuthorLi M(李密)
Affiliation1.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China
2.Department of Industrial and Manufacturing Systems Engineering, University of Hong Kong, Hong Kong
Recommended Citation
GB/T 7714
Li M,Liu LQ,Xi N,et al. Applications of Micro/Nano Automation Technology in Detecting Cancer Cells for Personalized Medicine[J]. IEEE TRANSACTIONS ON NANOTECHNOLOGY,2017,16(2):217-229.
APA Li M,Liu LQ,Xi N,&Wang YC.(2017).Applications of Micro/Nano Automation Technology in Detecting Cancer Cells for Personalized Medicine.IEEE TRANSACTIONS ON NANOTECHNOLOGY,16(2),217-229.
MLA Li M,et al."Applications of Micro/Nano Automation Technology in Detecting Cancer Cells for Personalized Medicine".IEEE TRANSACTIONS ON NANOTECHNOLOGY 16.2(2017):217-229.
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