SIA OpenIR  > 机器人学研究室
Modeling and analysis of living beating cardiomyocyte in sub-cell scale
Zhang C(张闯); Wang WX(王文学); Xi N(席宁); Wang YC(王越超); Liu LQ(刘连庆)
Department机器人学研究室
Conference Name17th IEEE International Conference on Nanotechnology, NANO 2017
Conference DateJuly 25-28, 2017
Conference PlacePittsburgh, PA, United states
Author of SourceIEEE Nanotechnology Council (NTC)
Source Publication2017 IEEE 17th International Conference on Nanotechnology, NANO 2017
PublisherIEEE
Publication PlaceNew York
2017
Pages406-410
Indexed ByEI ; CPCI(ISTP)
EI Accession number20180604700385
WOS IDWOS:000434647500094
Contribution Rank1
ISBN978-1-5090-3028-6
Abstract

The research on heart cells have attracted broad attention for the development of either heart disease therapy or muscle cell-based actuation for bio-syncretic robots. In order to study the mechanism and dynamics of beating activity of cardiomyocytes, many research methods have been proposed, such as the measurement of contractility and action potential of the cells. However, few of them has focused on the effect from the mechanical properties of sub-cell elements on the contraction performance of heart cells. In this work, a mechanical model of single heart cell was proposed based on the sub-cell structures, to study and control the contraction of the cardiomyocytes. The parameters of the parts in the theoretical model were identified with the cellular beating data obtained using Scanning Ion Conductance Microscopy (SICM) based on the derived mathematic model. Therefore, the contraction performance and the mechanical properties of sub-cell elements associated with the mechanical properties of parts in the model can be obtained for the further analysis of the relationship between the cell activity and sub-cell structures. This work is fundamental and meaningful for the research on cytobiology, heart mechanism and bio-syncretic robotics.

Language英语
Citation statistics
Document Type会议论文
Identifierhttp://ir.sia.cn/handle/173321/21544
Collection机器人学研究室
Corresponding AuthorWang WX(王文学); Liu LQ(刘连庆)
Affiliation1.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China
2.University of Chinese Academy of Sciences, Beijing 100049, China
3.Emerging Technologies Institute, Department of Industrial and Manufacturing Systems Engineering, University of Hong Kong, Pokfulam, Hong Kong
Recommended Citation
GB/T 7714
Zhang C,Wang WX,Xi N,et al. Modeling and analysis of living beating cardiomyocyte in sub-cell scale[C]//IEEE Nanotechnology Council (NTC). New York:IEEE,2017:406-410.
Files in This Item: Download All
File Name/Size DocType Version Access License
Modeling and analysi(451KB)会议论文 开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Zhang C(张闯)]'s Articles
[Wang WX(王文学)]'s Articles
[Xi N(席宁)]'s Articles
Baidu academic
Similar articles in Baidu academic
[Zhang C(张闯)]'s Articles
[Wang WX(王文学)]'s Articles
[Xi N(席宁)]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Zhang C(张闯)]'s Articles
[Wang WX(王文学)]'s Articles
[Xi N(席宁)]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Modeling and analysis of living beating cardiomyocyte in sub-cell scale.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.