SIA OpenIR  > 机器人学研究室
The Effect of Loading Rate on the Measurement of Cellular Viscoelasticity Properties with Atomic Force Microscopy
Wang B(王博); Wang WX(王文学); Wang YC(王越超); Liu B(刘斌); Liu LQ(刘连庆)
作者部门机器人学研究室
会议名称2017 7th International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)
会议日期Augest 7-11, 2017
会议地点Shanghai, CHINA
会议主办者Natl Nat Sci Fdn China, Minist Sci & Technol Peoples Republic of China, Minist Educ Peoples Republic of China, European Commiss, Res Execut Agcy, Jilin Provincial Sci & Technol Dept, IFToMM, Int Soc Nanomfg
会议录名称2017 IEEE INTERNATIONAL CONFERENCE ON MANIPULATION, MANUFACTURING AND MEASUREMENT ON THE NANOSCALE (3M-NANO)
出版者IEEE
出版地NEW YORK
2017
页码246-249
收录类别EI ; CPCI(ISTP)
EI收录号20182205249905
WOS记录号WOS:000426927300052
产权排序1
ISSN号2373-5422
ISBN号978-1-5386-1081-7
关键词Single Cell Dynamic Model Mechanical Properties Loading Rate Viscoelasticity Atomic Force Microscope
摘要

Organisms are composed by cells, and the cells can also reflect the physiology of creatures. The composition of a single cell and its cytoskeletal structure can be reflected by the mechanical properties of the cell. The cellular mechanical properties are correlated to the biological functions of the cell and its physiological activities. Therefore, establishing the mathematical model for the mechanical properties of single cells could provide the foundation for analyzing and regulating the physiological state of cells. In our previous work, we established a dynamical mathematical model with the viscose and elastic properties of single cells as the system parameters of the cellular system. The mathematical model can characterize the stress-relaxation phenomenon of a single cell, which is caused by an atomic force microscope (AFM). However, in this model, the effect of the loading rate of the AFM cantilever was neglected and all the stress-relaxation curves needed to be measured at a constant loading rate, in case that different loading rates would cause errors in the stress-relaxation curves. In this study, we discussed the effect of the loading rate on the measurement of cellular viscoelasticity properties with AFM. We clearly illustrated that the cellular stress-relaxation curves won't be effected by the loading rate of AFM when the loading rate is higher than a threshold. The stress-relaxation curves with the loading rate which is higher than the threshold can be used to extract viscoelasticity parameters more accurately.

语种英语
引用统计
文献类型会议论文
条目标识符http://ir.sia.cn/handle/173321/21653
专题机器人学研究室
通讯作者Wang WX(王文学); Liu LQ(刘连庆)
作者单位1.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences
2.University of Chinese Academy of Sciences, Beijing
推荐引用方式
GB/T 7714
Wang B,Wang WX,Wang YC,et al. The Effect of Loading Rate on the Measurement of Cellular Viscoelasticity Properties with Atomic Force Microscopy[C]//Natl Nat Sci Fdn China, Minist Sci & Technol Peoples Republic of China, Minist Educ Peoples Republic of China, European Commiss, Res Execut Agcy, Jilin Provincial Sci & Technol Dept, IFToMM, Int Soc Nanomfg. NEW YORK:IEEE,2017:246-249.
条目包含的文件 下载所有文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
The Effect of Loadin(417KB)会议论文 开放获取CC BY-NC-SA浏览 下载
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Wang B(王博)]的文章
[Wang WX(王文学)]的文章
[Wang YC(王越超)]的文章
百度学术
百度学术中相似的文章
[Wang B(王博)]的文章
[Wang WX(王文学)]的文章
[Wang YC(王越超)]的文章
必应学术
必应学术中相似的文章
[Wang B(王博)]的文章
[Wang WX(王文学)]的文章
[Wang YC(王越超)]的文章
相关权益政策
暂无数据
收藏/分享
文件名: The Effect of Loading Rate on the Measurement of Cellular Viscoelasticity Properties with Atomic Force Microscopy.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。