SIA OpenIR  > 机器人学研究室
Detecting the Micro/nano Physical Properties of Single Lymphoma Cells with Atomic Force Microscopy
Liu B(刘斌); Wei FN(魏发南); Li M(李密); Wang B(王博); Liu LQ(刘连庆)
Department机器人学研究室
Conference Name2017 7th International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)
Conference DateAugest 7-11, 2017
Conference PlaceShanghai, CHINA
Author of SourceNatl Nat Sci Fdn China, Minist Sci & Technol Peoples Republic of China, Minist Educ Peoples Republic of China, European Commiss, Res Execut Agcy, Jilin Provincial Sci & Technol Dept, IFToMM, Int Soc Nanomfg
Source Publication2017 IEEE INTERNATIONAL CONFERENCE ON MANIPULATION, MANUFACTURING AND MEASUREMENT ON THE NANOSCALE (3M-NANO)
PublisherIEEE
Publication PlaceNEW YORK
2017
Pages250-253
Indexed ByEI ; CPCI(ISTP)
EI Accession number20182205243257
WOS IDWOS:000426927300053
Contribution Rank1
ISSN2373-5422
ISBN978-1-5386-1081-7
KeywordAtomic Force Microscopy Lymphoma Image Elasticity Force Curve
Abstract

Non-Hodgkin's lymphoma (NHL) is the most common adult hematological cancer. With the advent of combination therapy of chemotherapy and the monoclonal anti-CD20 antibody Rituximab, the substantial advancement in the treatment of B-cell malignancies has been achieved. In the clinical treatment of NHL, however, there are still many patients who are not sensitive to the therapy of rituximab. Hence investigating the interactions between rituximab and lymphoma cells is crucial for us to understand the actions of rituximab and design drugs with better efficacies. Traditional biochemical methods for cell detection require the various pretreatments of the cell, destroying the structures of cells. This paper uses atomic force microscopy (AFM) to label-free characterize the micro/nano physical properties of single lymphoma cells, including cell morphology, cell elasticity, and molecular interactions on the cell surface. The study improved our understanding of the rituximab actions.

Language英语
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type会议论文
Identifierhttp://ir.sia.cn/handle/173321/21654
Collection机器人学研究室
Corresponding AuthorLiu B(刘斌)
Affiliation1.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences
2.School of Mechanical Engineering and Automation, Fuzhou University
Recommended Citation
GB/T 7714
Liu B,Wei FN,Li M,et al. Detecting the Micro/nano Physical Properties of Single Lymphoma Cells with Atomic Force Microscopy[C]//Natl Nat Sci Fdn China, Minist Sci & Technol Peoples Republic of China, Minist Educ Peoples Republic of China, European Commiss, Res Execut Agcy, Jilin Provincial Sci & Technol Dept, IFToMM, Int Soc Nanomfg. NEW YORK:IEEE,2017:250-253.
Files in This Item:
File Name/Size DocType Version Access License
Detecting the Micro (295KB)会议论文 开放获取CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Liu B(刘斌)]'s Articles
[Wei FN(魏发南)]'s Articles
[Li M(李密)]'s Articles
Baidu academic
Similar articles in Baidu academic
[Liu B(刘斌)]'s Articles
[Wei FN(魏发南)]'s Articles
[Li M(李密)]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Liu B(刘斌)]'s Articles
[Wei FN(魏发南)]'s Articles
[Li M(李密)]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Detecting the Micro nano Physical Properties of Single Lymphoma Cells with Atomic Force Microscopy.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.