SIA OpenIR  > 机器人学研究室
A Review of Nanoscale Characterizing Individual DNA Behaviors Using Atomic Force Microscopy
Li M(李密)1; Dang D(党丹)2; Xi N(席宁)1,3; Wang YC(王越超)1; Liu LQ(刘连庆)1
作者部门机器人学研究室
关键词Atomic Force Microscopy Nanoscale Dna Topography Dna Mechanics Dna Origami Nanorobotics
发表期刊IEEE TRANSACTIONS ON NANOTECHNOLOGY
ISSN1536-125X
2018
卷号17期号:5页码:920-933
收录类别SCI ; EI
EI收录号20181404982776
WOS记录号WOS:000443975800008
产权排序1
资助机构National Natural Science Foundation of China ; Youth Innovation Promotion Association CAS ; CAS FEA International Partnership Program for Creative Research Teams
摘要

Deoxyribonucleic acid (DNA), the structural basis of genetics, plays a crucial role in the life of cells. The abnormal behaviors of DNA are closely related to the pathological changes of living organisms. The advent of atomic forcemicroscopy (AFM) provides an exciting instrument for biophysically probing the nanoscale dynamic activities of the individual native molecules, considerably complementing the results obtained by traditional biochemical population-averaged measurements. In the past decades, AFM has been widely used in DNA studies, significantly providing novel insights into molecular biology. In this paper, the methodologies and progresses of utilizing AFM to characterize the behaviors of individual DNA molecules from several facets (including DNA topography imaging, DNA mechanics measurements, DNA origami, and DNA nanorobotics) are reviewed, and the future directions are discussed.

语种英语
WOS类目Engineering, Electrical & Electronic ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied
关键词[WOS]Ii Restriction Endonucleases ; Nucleotide Excision-repair ; Single-molecule Force ; Plasmid Dna ; Persistence Length ; Magnetic Tweezers ; Protein Complexes ; Optical Tweezers ; Delivery-system ; Mismatch Repair
WOS研究方向Engineering ; Science & Technology - Other Topics ; Materials Science ; Physics
资助项目National Natural Science Foundation of China[61503372] ; National Natural Science Foundation of China[61522312] ; National Natural Science Foundation of China[U1613220] ; National Natural Science Foundation of China[61433017] ; National Natural Science Foundation of China[61504072] ; Youth Innovation Promotion Association CAS[2017243] ; CAS FEA International Partnership Program for Creative Research Teams
引用统计
文献类型期刊论文
条目标识符http://ir.sia.cn/handle/173321/21730
专题机器人学研究室
通讯作者Li M(李密)
作者单位1.State Key Laboratory of Robotics, Shenyang Institute of Automation, Shenyang 110016, China
2.School of Medical Devices, Shenyang Pharmaceutical University, Shenyang 110016, China
3.Department of Industrial and Manufacturing Systems Engineering, The University of Hong Kong, Hong Kong, China
推荐引用方式
GB/T 7714
Li M,Dang D,Xi N,et al. A Review of Nanoscale Characterizing Individual DNA Behaviors Using Atomic Force Microscopy[J]. IEEE TRANSACTIONS ON NANOTECHNOLOGY,2018,17(5):920-933.
APA Li M,Dang D,Xi N,Wang YC,&Liu LQ.(2018).A Review of Nanoscale Characterizing Individual DNA Behaviors Using Atomic Force Microscopy.IEEE TRANSACTIONS ON NANOTECHNOLOGY,17(5),920-933.
MLA Li M,et al."A Review of Nanoscale Characterizing Individual DNA Behaviors Using Atomic Force Microscopy".IEEE TRANSACTIONS ON NANOTECHNOLOGY 17.5(2018):920-933.
条目包含的文件 下载所有文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
A Review of Nanoscal(4970KB)期刊论文作者接受稿开放获取CC BY-NC-SA浏览 下载
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Li M(李密)]的文章
[Dang D(党丹)]的文章
[Xi N(席宁)]的文章
百度学术
百度学术中相似的文章
[Li M(李密)]的文章
[Dang D(党丹)]的文章
[Xi N(席宁)]的文章
必应学术
必应学术中相似的文章
[Li M(李密)]的文章
[Dang D(党丹)]的文章
[Xi N(席宁)]的文章
相关权益政策
暂无数据
收藏/分享
文件名: A Review of Nanoscale Characterizing Individual DNA Behaviors Using Atomic Force Microscopy.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。