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Modeling the Viscoelastic Properties of Living Cells by Considering the Cantilever Effect
Wang B(王博)1,2; Wang WX(王文学)1; Wang YC(王越超)1; Liu B(刘斌); Liu LQ(刘连庆)1
作者部门机器人学研究室
会议名称7th IEEE Annual International Conference on CYBER Technology in Automation, Control, and Intelligent Systems, CYBER 2017
会议日期July 31 - August 4, 2017
会议地点Hawaii, USA
会议主办者IEEE Robotics and Automation Society
会议录名称2017 IEEE 7th Annual International Conference on CYBER Technology in Automation, Control, and Intelligent Systems, CYBER 2017
出版者IEEE
出版地New York
2017
页码295-299
收录类别EI ; CPCI(ISTP)
EI收录号20183905873462
WOS记录号WOS:000447628700055
产权排序1
ISBN号978-1-5386-0489-2
关键词Single Cell Dynamic Model Mechanical Properties Atomic Force Microscopy Viscoelasticity
摘要

Cells are the basic component units of organisms, and reflect the physiological state of creatures. The mechanical properties of a cell reflect the cytoskeletal structure and composition and are closely related to the cellular biological functions and physiological activities. Therefore, modeling the mechanical properties of single cells provides the basis for analyzing and controlling the cellular state. Previously, we developed a dynamical model with cellular viscoelasticity properties as the system parameters to describe the stress-relaxation phenomenon of a single cell indented by an atomic force microscope (AFM). However, in this model, the effect of the AFM cantilever was neglected and the viscoelastic properties of both the cell and the AFM cantilever are considered as a whole in the model. In this study, we modified the model by considering the AFM cantilever as an independent factor and the elasticity of AFM cantilever and the viscoelasticity of cells are decoupled. The modified model can characterize the mechanical properties of single cells without the influence of AFM cantilever.

语种英语
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文献类型会议论文
条目标识符http://ir.sia.cn/handle/173321/22847
专题机器人学研究室
通讯作者Wang WX(王文学); Liu LQ(刘连庆)
作者单位1.State Key Laboratory of Robotics, Chinese Academy of Sciences, Shenyang Institute of Automation, Shenyang 110016, China
2.University of Chinese Academy of Sciences, Beijing 100049, China
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Wang B,Wang WX,Wang YC,et al. Modeling the Viscoelastic Properties of Living Cells by Considering the Cantilever Effect[C]//IEEE Robotics and Automation Society. New York:IEEE,2017:295-299.
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