Modeling the Viscoelastic Properties of Living Cells by Considering the Cantilever Effect | |
Wang B(王博)1,2![]() ![]() ![]() ![]() | |
Department | 机器人学研究室 |
Conference Name | 7th IEEE Annual International Conference on CYBER Technology in Automation, Control, and Intelligent Systems, CYBER 2017 |
Conference Date | July 31 - August 4, 2017 |
Conference Place | Hawaii, USA |
Author of Source | IEEE Robotics and Automation Society |
Source Publication | 2017 IEEE 7th Annual International Conference on CYBER Technology in Automation, Control, and Intelligent Systems, CYBER 2017 |
Publisher | IEEE |
Publication Place | New York |
2017 | |
Pages | 295-299 |
Indexed By | EI ; CPCI(ISTP) |
EI Accession number | 20183905873462 |
WOS ID | WOS:000447628700055 |
Contribution Rank | 1 |
ISBN | 978-1-5386-0489-2 |
Keyword | Single Cell Dynamic Model Mechanical Properties Atomic Force Microscopy Viscoelasticity |
Abstract | Cells are the basic component units of organisms, and reflect the physiological state of creatures. The mechanical properties of a cell reflect the cytoskeletal structure and composition and are closely related to the cellular biological functions and physiological activities. Therefore, modeling the mechanical properties of single cells provides the basis for analyzing and controlling the cellular state. Previously, we developed a dynamical model with cellular viscoelasticity properties as the system parameters to describe the stress-relaxation phenomenon of a single cell indented by an atomic force microscope (AFM). However, in this model, the effect of the AFM cantilever was neglected and the viscoelastic properties of both the cell and the AFM cantilever are considered as a whole in the model. In this study, we modified the model by considering the AFM cantilever as an independent factor and the elasticity of AFM cantilever and the viscoelasticity of cells are decoupled. The modified model can characterize the mechanical properties of single cells without the influence of AFM cantilever. |
Language | 英语 |
Citation statistics | |
Document Type | 会议论文 |
Identifier | http://ir.sia.cn/handle/173321/22847 |
Collection | 机器人学研究室 |
Corresponding Author | Wang WX(王文学); Liu LQ(刘连庆) |
Affiliation | 1.State Key Laboratory of Robotics, Chinese Academy of Sciences, Shenyang Institute of Automation, Shenyang 110016, China 2.University of Chinese Academy of Sciences, Beijing 100049, China |
Recommended Citation GB/T 7714 | Wang B,Wang WX,Wang YC,et al. Modeling the Viscoelastic Properties of Living Cells by Considering the Cantilever Effect[C]//IEEE Robotics and Automation Society. New York:IEEE,2017:295-299. |
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Modeling the Viscoel(624KB) | 会议论文 | 开放获取 | CC BY-NC-SA | View Application Full Text |
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