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Modeling the Viscoelastic Properties of Living Cells by Considering the Cantilever Effect
Wang B(王博)1,2; Wang WX(王文学)1; Wang YC(王越超)1; Liu B(刘斌); Liu LQ(刘连庆)1
Department机器人学研究室
Conference Name7th IEEE Annual International Conference on CYBER Technology in Automation, Control, and Intelligent Systems, CYBER 2017
Conference DateJuly 31 - August 4, 2017
Conference PlaceHawaii, USA
Author of SourceIEEE Robotics and Automation Society
Source Publication2017 IEEE 7th Annual International Conference on CYBER Technology in Automation, Control, and Intelligent Systems, CYBER 2017
PublisherIEEE
Publication PlaceNew York
2017
Pages295-299
Indexed ByEI ; CPCI(ISTP)
EI Accession number20183905873462
WOS IDWOS:000447628700055
Contribution Rank1
ISBN978-1-5386-0489-2
KeywordSingle Cell Dynamic Model Mechanical Properties Atomic Force Microscopy Viscoelasticity
Abstract

Cells are the basic component units of organisms, and reflect the physiological state of creatures. The mechanical properties of a cell reflect the cytoskeletal structure and composition and are closely related to the cellular biological functions and physiological activities. Therefore, modeling the mechanical properties of single cells provides the basis for analyzing and controlling the cellular state. Previously, we developed a dynamical model with cellular viscoelasticity properties as the system parameters to describe the stress-relaxation phenomenon of a single cell indented by an atomic force microscope (AFM). However, in this model, the effect of the AFM cantilever was neglected and the viscoelastic properties of both the cell and the AFM cantilever are considered as a whole in the model. In this study, we modified the model by considering the AFM cantilever as an independent factor and the elasticity of AFM cantilever and the viscoelasticity of cells are decoupled. The modified model can characterize the mechanical properties of single cells without the influence of AFM cantilever.

Language英语
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type会议论文
Identifierhttp://ir.sia.cn/handle/173321/22847
Collection机器人学研究室
Corresponding AuthorWang WX(王文学); Liu LQ(刘连庆)
Affiliation1.State Key Laboratory of Robotics, Chinese Academy of Sciences, Shenyang Institute of Automation, Shenyang 110016, China
2.University of Chinese Academy of Sciences, Beijing 100049, China
Recommended Citation
GB/T 7714
Wang B,Wang WX,Wang YC,et al. Modeling the Viscoelastic Properties of Living Cells by Considering the Cantilever Effect[C]//IEEE Robotics and Automation Society. New York:IEEE,2017:295-299.
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