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Investigations of cellular and molecular biophysical properties by atomic force microscopy nanorobotics
LI M(李密)
PublisherSpringer Nature
Publication PlaceSingapore
Contribution Rank1
AbstractThis book presents methodological and application research in detecting cellular and molecular biophysical properties based on atomic force microscopy (AFM) nanorobotics. Series methods for in situ label-free visualizing and quantifying the multiple physical properties of single cells and single molecules were developed, including immobilization strategies for observing fine structures of living cells, measurements of single-cell mechanics, force recognition of molecular interactions, and mapping protein organizations on cell surface. The biomedical applications of these methods in clinical lymphoma treatments were explored in detail, including primary sample preparation, cancer cell recognition, AFM detection and data analysis. Future directions about the biomedical applications of AFM are also given.
Document Type专著
AffiliationState Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China
First Author AffilicationShenyang Institute of Automation, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
LI M. Investigations of cellular and molecular biophysical properties by atomic force microscopy nanorobotics[M]. Singapore:Springer Nature,2018.
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