A considerable number of studies have focused on fabrication of hydrogel microstructures due to its wide applications in tissue engineering, drug delivery, and extracellular matrix construction. Here, we introduce a hydrogel printing method based on UV-induced projection via a digital micromirror device (DMD). Arbitrary microstructures could be fabricated within few seconds (<3) by modulating UV projection using DMD as digital dynamic masks instead of a physical mask, which also offers a high degree of flexibility and repeatability. Furthermore, the ability of PEGDA film to hinder cell adhesion makes it possible to control area over which cells attach.
State Key Laboratory of Robotics, Shenyang Institute of AutomationChinese Academy of Sciences, Shenyang, China
Recommended Citation GB/T 7714
Yang WG,Yu HB,Wang YC,et al. Hydrogel Printing Based on UV-Induced Projection for Cell-Based Microarray Fabrication. Cell-Based Microarrays: Methods and Protocols, Methods in Molecular Biology. New York, NY:Humana Press,2018:97-105.