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Fabrication of flexible microlens arrays for parallel super-resolution imaging
Zhang TY(张天尧)1,2,3; Li P(李盼)1,2,3; Yu HB(于海波)1,2; Wang FF(王飞飞)1,2,4; Wang XD(王晓朵)1,2; Yang T(杨铁)1,2; Yang WG(杨文广)5; Li WJ(李文荣)1,2,6; Wang YC(王越超)1,2; Liu LQ(刘连庆)1,2
Department机器人学研究室
Corresponding AuthorYu, Haibo(yuhaibo@sia.cn) ; Liu, Lianqing(lqliu@sia.cn)
Source PublicationApplied Surface Science
ISSN0169-4332
2020
Volume504Pages:1-10
Indexed BySCI ; EI
EI Accession number20194807737498
WOS IDWOS:000502040600137
Contribution Rank1
Funding OrganizationNational Natural Science Foundation of China (Project No. 61727811, 61803323, 61433017, 61503258 and U1613220) ; Instrument Developing Project of the Chinese Academy of Sciences (Grant No. YZ201649) ; CAS FEA International Partnership Program for Creative Research Teams ; Youth Innovation Promotion Association CAS (Project No. 2015160) ; Hong Kong Research Grants Council (Project No. CityU 11205415)
KeywordMicrolens array Super-resolution imaging PDMS Optical microscopy Microsphere
Abstract

The development of optical microscopy has greatly promoted the progress of biological fields, providing outstanding observation tools for genetics, molecular biology, and bioengineering technology, from the macro- to the micro-scale. Owing to the optical diffraction limit, the imaging resolution of traditional optical microscopy is limited. Recently, the use of microspheres has been demonstrated to aid the capability to realize super-resolution imaging under white light illumination; however, using this approach, the imaging field of view is only a few microns, due to the size of the microspheres. In this paper, we fabricated microlens arrays by embedding microspheres into polydimethylsiloxane (PDMS) films. Using this method, we have successfully achieved parallel imaging under the sub-diffraction-limited resolution using multiple microspheres with a magnification up to ×2.59–×2.99, and the observed results are consistent with finite-difference time-domain (FDTD) simulation results. Furthermore, two imaging modes were developed: the microlens array-based dynamic scanning imaging mode and the stochastic microlens array region imaging overlay reconstruction mode, a surface image of 900 μm2 was presented stitched with 210 images. This study combines the advantages of parallel imaging and dynamic imaging to increase efficiency and observation range. © 2019

Language英语
WOS SubjectChemistry, Physical ; Materials Science, Coatings & Films ; Physics, Applied ; Physics, Condensed Matter
WOS KeywordMICROSCOPY ; RESOLUTION ; MICROSPHERES ; NANOJET ; BACKSCATTERING ; NANOPARTICLES ; LIMIT
WOS Research AreaChemistry ; Materials Science ; Physics
Funding ProjectNational Natural Science Foundation of China[61727811] ; National Natural Science Foundation of China[61803323] ; National Natural Science Foundation of China[61433017] ; National Natural Science Foundation of China[61503258] ; National Natural Science Foundation of China[U1613220] ; Instrument Developing Project of the Chinese Academy of Sciences[YZ201649] ; CAS FEA International Partnership Program for Creative Research Teams ; Youth Innovation Promotion Association CAS[2015160] ; Hong Kong Research Grants Council[CityU 11205415]
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Cited Times:4[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sia.cn/handle/173321/25929
Collection机器人学研究室
Corresponding AuthorYu HB(于海波); Liu LQ(刘连庆)
Affiliation1.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China
2.Institutes for Robotics and Intelligent Manufacturing, Chinese Academy of Sciences, Shenyang 110016, China
3.University of the Chinese Academy of Sciences, Beijing 100049, China
4.Department of Chemistry, Stanford University, Stanford, United States
5.School of Electromechanical and Automotive Engineering Yantai University, China
6.Department of Mechanical Engineering, City University of Hong Kong, Hong Kong
Recommended Citation
GB/T 7714
Zhang TY,Li P,Yu HB,et al. Fabrication of flexible microlens arrays for parallel super-resolution imaging[J]. Applied Surface Science,2020,504:1-10.
APA Zhang TY.,Li P.,Yu HB.,Wang FF.,Wang XD.,...&Liu LQ.(2020).Fabrication of flexible microlens arrays for parallel super-resolution imaging.Applied Surface Science,504,1-10.
MLA Zhang TY,et al."Fabrication of flexible microlens arrays for parallel super-resolution imaging".Applied Surface Science 504(2020):1-10.
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