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Dynamic fabrication of microfluidic systems for particles separation based on optical projection lithography
Sun LJ(孙路静)1; Yang WG(杨文广)1; Chu HH(褚洪汇)1; Yang, Rendi1; Yu HB(于海波)2,3
Department机器人学研究室
Source PublicationBiomedical Microdevices
ISSN1387-2176
2020
Volume22Issue:4Pages:1-7
Indexed BySCI ; EI
EI Accession number20204609476804
WOS IDWOS:000592415300001
Contribution Rank2
Funding OrganizationNational Natural Science Foundation of China (Project No. 61803323), Shandong Province Higher Educational Science and Technology Program (Project No.J18KA380) and Natural Science Foundation of Shandong Province (Project No. ZR2019BF049)
KeywordParticles separation Microfluidic technology Optical projection lithography
Abstract

Microfluidic systems are widely used for applications in biology, medicine and chemistry. Particles separation by microfluidics is a scientific subject that requires ongoing research efforts. In this article, we demonstrate a micropillar-based particles separator fabricated using digital micromirror device (DMD)-based optical projection lithography from the perspectives of theory, design, simulation and experiments. Micropillars can be fabricated with customized shapes and sizes which shows high flexible and efficient. The particles separator employs the physical separation of a cylindrical array, a rectangular array, or a triangular array to separate particles. The simulation and experiment results indicate that the device with different micropillars could achieve separation of 20 and 200 μm polystyrene microspheres. Furthermore, the separation efficiency depended on flow rate and the shape of micropillars. All the results can be used to support the redesign of microfluidic structures to address particles separation needs.

Language英语
WOS SubjectEngineering, Biomedical ; Nanoscience & Nanotechnology
WOS KeywordDIGITAL MICROFLUIDICS ; LABEL-FREE ; DEVICE ; BLOOD ; CELLS ; CHIP
WOS Research AreaEngineering ; Science & Technology - Other Topics
Funding ProjectNational Natural Science Foundation of China[61803323] ; Shandong Province Higher Educational Science and Technology Program ; Natural Science Foundation of Shandong Province[ZR2019BF049]
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sia.cn/handle/173321/27902
Collection机器人学研究室
Corresponding AuthorYang WG(杨文广)
Affiliation1.School of Electromechanical and Automotive Engineering, Yantai University, Yantai 264005, China
2.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China
3.Institutes for Robotics and Intelligent Manufacturing, Chinese Academy of Sciences, Shenyang 110016, China
Recommended Citation
GB/T 7714
Sun LJ,Yang WG,Chu HH,et al. Dynamic fabrication of microfluidic systems for particles separation based on optical projection lithography[J]. Biomedical Microdevices,2020,22(4):1-7.
APA Sun LJ,Yang WG,Chu HH,Yang, Rendi,&Yu HB.(2020).Dynamic fabrication of microfluidic systems for particles separation based on optical projection lithography.Biomedical Microdevices,22(4),1-7.
MLA Sun LJ,et al."Dynamic fabrication of microfluidic systems for particles separation based on optical projection lithography".Biomedical Microdevices 22.4(2020):1-7.
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