SIA OpenIR  > 光电信息技术研究室
A Novel Evolution Strategy of Level Set Method for the Segmentation of Overlapping Cervical Cells
Liu GQ(刘广琦); Ding QH(丁庆海); Luo HB(罗海波); Ju MR(鞠默然); Jin TM(金天明); He M(何淼); Dong G(董刚)
Department光电信息技术研究室
Source PublicationAPPLIED SCIENCES-BASEL
ISSN2076-3417
2021
Volume11Issue:1Pages:1-23
Indexed BySCI
WOS IDWOS:000605870700001
Contribution Rank1
Keywordcervical cell image segmentation level set method ISBI topology filtering
Abstract

Development of an accurate and automated algorithm to completely segment cervical cells in Pap images is still one of the most challenging tasks. The main reasons are the presence of overlapping cells and the lack of guiding mechanism for the convergence of ill-defined contours to the actual cytoplasm boundaries. In this paper, we propose a novel method to address these problems based on level set method (LSM). Firstly, we proposed a morphological scaling-based topology filter (MSTF) and derived a new mathematical toolbox about vector calculus for evolution of level set function (LSF). Secondly, we combine MSTF and the mathematical toolbox into a multifunctional filtering algorithm 2D codimension two-object level set method (DCTLSM) to split touching cells. The DCTLSM can morphologically scale up and down the contour while keeping part of the contour points fixed. Thirdly, we design a contour scanning strategy as the evolution method of LSF to segment overlapping cells. In this strategy, a cutting line can be detected by morphologically scaling the union LSF of the pairs of cells. Then, we used this cutting line to construct a velocity field with an effective guiding mechanism for attracting and repelling LSF. The performance of the proposed algorithm was evaluated quantitatively and qualitatively on the ISBI-2014 dataset. The experimental results demonstrated that the proposed method is capable of fully segmenting cervical cells with superior segmentation accuracy compared with recent peer works.

Language英语
WOS SubjectChemistry, Multidisciplinary ; Engineering, Multidisciplinary ; Materials Science, Multidisciplinary ; Physics, Applied
WOS KeywordNUCLEUS SEGMENTATION ; ACCURATE SEGMENTATION ; CYTOPLASM ; CYTOLOGY ; DISTANCE ; IMAGES ; ALGORITHMS
WOS Research AreaChemistry ; Engineering ; Materials Science ; Physics
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sia.cn/handle/173321/28213
Collection光电信息技术研究室
Corresponding AuthorLuo HB(罗海波)
Affiliation1.Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China
2.Institutes for Robotics and Intelligent Manufacturing, Chinese Academy of Sciences, Shenyang 110169, China
3.University of Chinese Academy of Sciences, Beijing 100049, China
4.Key Laboratory of Opto-Electronic Information Processing, Chinese Academy of Science, Shenyang 110016, China
5.The Key Laboratory of Image Understanding and Computer Vision, Shenyang 110016, China
6.Space Star Technology Company, Ltd., Beijing 100086, China
Recommended Citation
GB/T 7714
Liu GQ,Ding QH,Luo HB,et al. A Novel Evolution Strategy of Level Set Method for the Segmentation of Overlapping Cervical Cells[J]. APPLIED SCIENCES-BASEL,2021,11(1):1-23.
APA Liu GQ.,Ding QH.,Luo HB.,Ju MR.,Jin TM.,...&Dong G.(2021).A Novel Evolution Strategy of Level Set Method for the Segmentation of Overlapping Cervical Cells.APPLIED SCIENCES-BASEL,11(1),1-23.
MLA Liu GQ,et al."A Novel Evolution Strategy of Level Set Method for the Segmentation of Overlapping Cervical Cells".APPLIED SCIENCES-BASEL 11.1(2021):1-23.
Files in This Item:
File Name/Size DocType Version Access License
A Novel Evolution St(8515KB)期刊论文出版稿开放获取CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Liu GQ(刘广琦)]'s Articles
[Ding QH(丁庆海)]'s Articles
[Luo HB(罗海波)]'s Articles
Baidu academic
Similar articles in Baidu academic
[Liu GQ(刘广琦)]'s Articles
[Ding QH(丁庆海)]'s Articles
[Luo HB(罗海波)]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Liu GQ(刘广琦)]'s Articles
[Ding QH(丁庆海)]'s Articles
[Luo HB(罗海波)]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: A Novel Evolution Strategy of Level Set Method for the Segmentation of Overlapping Cervical Cells.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.