SIA OpenIR  > 机器人学研究室
Recent Advances in Three-Dimensional Multicellular Spheroid Culture and Future Development
Shen, Honglin1; Cai SX(蔡树向)1; Wu, Chuanxiang1; Yang WG(杨文广)1; Yu HB(于海波)2; Liu LQ(刘连庆)2
Department机器人学研究室
Source PublicationMICROMACHINES
ISSN2072-666X
2021
Volume12Issue:1Pages:1-21
Indexed BySCI ; EI
EI Accession number20210609901055
WOS IDWOS:000610518200001
Contribution Rank2
Funding OrganizationNational Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [61803323] ; Natural Science Foundation of Shandong ProvinceNatural Science Foundation of Shandong Province [ZR2019BF049]
Keywordcell spheroids three-dimensional cell culture tissue engineering
Abstract

Three-dimensional multicellular spheroids (MCSs) have received extensive attention in the field of biomedicine due to their ability to simulate the structure and function of tissues in vivo more accurately than traditional in vitro two-dimensional models and to simulate cell-cell and cell extracellular matrix (ECM) interactions. It has become an important in vitro three-dimensional model for tumor research, high-throughput drug screening, tissue engineering, and basic biology research. In the review, we first summarize methods for MCSs generation and their respective advantages and disadvantages and highlight the advances of hydrogel and microfluidic systems in the generation of spheroids. Then, we look at the application of MCSs in cancer research and other aspects. Finally, we discuss the development direction and prospects of MCSs

Language英语
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sia.cn/handle/173321/28316
Collection机器人学研究室
Corresponding AuthorYang WG(杨文广)
Affiliation1.School of Electromechanical and Automotive Engineering, Yantai University, Yantai 264005, China
2.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China
Recommended Citation
GB/T 7714
Shen, Honglin,Cai SX,Wu, Chuanxiang,et al. Recent Advances in Three-Dimensional Multicellular Spheroid Culture and Future Development[J]. MICROMACHINES,2021,12(1):1-21.
APA Shen, Honglin,Cai SX,Wu, Chuanxiang,Yang WG,Yu HB,&Liu LQ.(2021).Recent Advances in Three-Dimensional Multicellular Spheroid Culture and Future Development.MICROMACHINES,12(1),1-21.
MLA Shen, Honglin,et al."Recent Advances in Three-Dimensional Multicellular Spheroid Culture and Future Development".MICROMACHINES 12.1(2021):1-21.
Files in This Item:
File Name/Size DocType Version Access License
Recent Advances in T(3920KB)期刊论文出版稿开放获取CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Shen, Honglin]'s Articles
[Cai SX(蔡树向)]'s Articles
[Wu, Chuanxiang]'s Articles
Baidu academic
Similar articles in Baidu academic
[Shen, Honglin]'s Articles
[Cai SX(蔡树向)]'s Articles
[Wu, Chuanxiang]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Shen, Honglin]'s Articles
[Cai SX(蔡树向)]'s Articles
[Wu, Chuanxiang]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Recent Advances in Three-Dimensional Multicellular Spheroid Culture and Future Development.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.