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Inducing self-rotation of Melan-a cells by ODEP
Chau, Long-Ho; Ouyang, Mengxing; Liang WF(梁文峰); Lee, Gwo-Bin; Li WJ(李文荣); Liu, W.K
作者部门机器人学研究室
会议名称7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2012
会议日期March 5-8, 2012
会议地点Kyoto, Japan
会议主办者IEEE; IEEE Nanotechnology Council; The Murata Science Foundation; The Kyoto University Foundation; Office of Naval Research Global
会议录名称2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2012
出版者IEEE Computer Society
出版地Piscataway, NJ
2012
页码195-199
收录类别EI
EI收录号20122215078267
产权排序2
ISBN号978-1-4673-1124-3
关键词Cytology Dielectric Devices Microfluidics Rotation
摘要

This paper presents our discovery that self-rotation of Melan-a pigment cells can be induced by applying appropriate optical dielectrophoretic (ODEP) parameters. Under optically induced DEP force, which is generated by specific optical electrode patterns and with a band-width of AC bias frequencies, Melan-a cells can be trapped or repelled away from the optical electrodes. In addition, the self-rotation motion of the Melan-a cells was observed. In particular, the applied frequency and voltage dominate the overall cell motion. Hence, the cells can be manipulated on an electrode-free surface. This project studies the rotation and translation motions of the cells in an ODEP system. We speculate that the unbalanced distribution of melanin inside the pigment cells causes this self-rotation phenomenon. Therefore, both pigment cells (Melan-a) and non-pigment cells (Raw 264.7) have been tested in the ODEP experiments to compare their motion behavior. Potential applications for this novel observation are to use the self-rotation phenomenon to elucidate the pigment cells' physical property, and separate the pigment and non-pigment cells. 

语种英语
文献类型会议论文
条目标识符http://ir.sia.cn/handle/173321/9875
专题机器人学研究室
作者单位1.Centre for Micro and Nano Systems, Chinese University of Hong Kong, Hong Kong, Hong Kong
2.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, China
3.Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan
4.Department of Mechanical and Biomedical Engineering, City University of Hong Kong, Hong Kong
5.Department of Anatomy, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, Hong Kong
推荐引用方式
GB/T 7714
Chau, Long-Ho,Ouyang, Mengxing,Liang WF,et al. Inducing self-rotation of Melan-a cells by ODEP[C]//IEEE; IEEE Nanotechnology Council; The Murata Science Foundation; The Kyoto University Foundation; Office of Naval Research Global. Piscataway, NJ:IEEE Computer Society,2012:195-199.
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